PUBLIC HEALTH AND INTELLECTUAL PROPERTY

 

How would you persuade someone to be tested for HIV-AIDS if you had nothing to offer but stigmatization?  Early in the epidemic this was the problem in the United States.  It is still a major problem in the underdeveloped world because the expense of treatment is out of the question for the vast majority of people there.  Treatment, although not curative, greatly prolongs useful life for persons with HIV-AIDS here in the United States.  Widespread testing of high-risk groups also promotes education for prevention, where a given effort has the greatest effect. 

 

The World Trade Organization (WTO) has a protocol which they hope will be ratified by all participating countries (including the most underdeveloped) by 2006. This protocol is called TRIPS and stands for Trade and International Property Rights Agreement.  TRIPS would cast in stone the unsatisfactory dilemma described in the beginning of this article. In other words after 2006 there would be no legal exceptions to patent protection of essential drugs even  for vital public health uses anywhere in the world.

 

The Department for International Development of The British government set up a commission to study the consequences of TRIPS.  The report prepared by this commission, recently released, states unequivocally that patents in the area of public health can be bad for poor countries.  The commission had lawyers, scientists, a bio-ethicist, and a senior executive from Pfizer (a drug company) as a member.  Presumably the Pfizer executive’s presence on the commission indicates that the radical remedies of the report would not do serious harm to the pharmaceutical industry.  Clare Short, Secretary of the British Agency for International Development, and her Agency seem pleased with the report which recommends compulsory licensing for manufacture of generic versions of patented drugs deemed necessary for public health purposes.  Reality requires permitting the export of such licensed drugs to underdeveloped countries unable to manufacture these products within their own borders.  Some countries, such as India, are already exporting such drugs.  The recommended amendments to TRIPS would extend this activity beyond 2006.

 

It is encouraging that GlaxoSmithKline is already shipping reduced price AIDS drugs to Africa before any formal change in the TRIPS protocol has been ratified.  Also noteworthy: since 1987 Merck has been donating ivermectin throughout the endemic area in Africa for river blindness with the intention of wiping out the disease.

 

Malaria and tuberculosis (particularly the multi-drug resistant variety) are in both cases widespread and research for treatments is under-funded because of lack of affluent customers.  They are basically poor people’s diseases today although malaria could affect North America by way of global warming or inadvertent importing of exotic vectors (in malaria’s case--mosquitoes).  Malaria was present in southeast United states 50 to 100 years ago from Texas to New Jersey.  An exotic vector mosquito plays a role in the current outbreak of West Nile fever as well: Aedes albopictus (Asian tiger mosquito) probably brought over in rain water in second hand tires on the deck of a freighter.  Donor funding for malaria control is $100 to $200 million per year including funding of $30 million per year from the Gates Foundation estimated to produce about one new anti-malarial drug every five years ($150 million per drug) and the commitment is long term. But there are myriad small, boring chores that only public funding can seem to accomplish over time, for instance, re-dipping bed nets in insecticide about every six months.  People don’t seem to get around to doing such things unless they are organized to be convenient.  So, public health funding does not lend itself to privatization.  The Center for Disease Control (CDC) in Atlanta and state labs of hygiene are being beefed up in response to the bioterrorism threat.  After all, at the beginning of an epidemic public health activities are the same whether the epidemic is caused by bio-terrorism or not.

 

World Health Organization (WHO) has done some remarkable things that include ridding the world of small pox (and very nearly doing the same with poliomyelitis).  It has been under very competent management for some time and, if adequately funded, should play an increasing part in keeping us safe.  I speak as a physician with an interest in public health.

 

 

John A. Frantz, M.D.

October 18, 2002

 

 

                                     Perverbs   are  doctored   up   Proverbs

 

              One man’s Mede is another man’s Persian                              One man’s meat is another man’s poison.

 

             Too many crooks spoil the brothel.                                       Too many cooks spoil the broth.

 

             Many are cold but few are frozen (for sex                                Many are called but few are chosen.

             therapists)    .

        

             All jack and no work makes a dull playboy.                               All work and no play makes Jack a dull boy.

 

             All work and no play makes jack (archaic slang for money).        

 

             A man’s best friend is his dogma.                                            Obvious

 

             Many hands make light work harder                                                 

  

            Rush fools in where angels fear to tread                                     Devised by a friend of a signer of The

                                                                                              Declaration of Independence

 

            Partying is such sweet sorrow (subsequent                                 Parting is such sweet sorrow.

            hangover).

 

            You can lead a horticulture, but you can’t                                  You can lead a horse to water, but you can’t

            make ‘em think.                                                                make him drink. 

 

            This last one isn’t a perverb, but it is close.                               An Irish pervert likes women better than he likes whiskey

 

The author discovered perverbs in the mathematics and puzzles section of the old ScientificAmerican 

Magazine.  Perverbs make a nice minor hobby.  Only some of the above are original.

January 23, 2003.